EXOSC5 exosome component 5 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 56915)
Symbol: EXOSC5
Full name: exosome component 5
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: CABAC; RRP41B; RRP46; Rrp46p; hRrp46p; p12B
Summary: Predicted to enable RNA binding activity. Involved in DNA deamination and exonucleolytic catabolism of deadenylated mRNA. Acts upstream of or within defense response to virus. Located in nucleolus; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in lymph node (RPKM 8.8), ovary (RPKM 8.2) and 25 other tissues
Orthologs: mouse
Gene size: 10986bp
Exon count: 6