Pus1 pseudouridine synthase 1 [ Mus musculus (house mouse) ] - Gene - Data resources

56361

Pus1 pseudouridine synthase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 56361)

Symbol: Pus1

Full name: pseudouridine synthase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: A730013B20Rik; MPUS1; mPus1p

Summary: Enables chromatin binding activity; nuclear receptor coactivator activity; and tRNA pseudouridine synthase activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and tRNA pseudouridine synthesis. Located in nucleolus. Part of transcription regulator complex. Used to study myopathy, lactic acidosis, and sideroblastic anemia. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 1. Orthologous to human PUS1 (pseudouridine synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in large intestine adult (RPKM 13.1), liver E14 (RPKM 13.0) and 28 other tissues

Orthologs: human

Gene size: 6991bp

Exon count: 7