Full name: olfactomedin 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: AMY; Noe1; OlfA; Pancortin; Pancortin3

Summary: Enables amyloid-beta binding activity and identical protein binding activity. Involved in neuronal signal transduction and regulation of axon extension. Acts upstream of or within negative regulation of amyloid-beta formation and negative regulation of neuron migration. Located in several cellular components, including axonal growth cone; neuronal cell body; and synaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is extrinsic component of synaptic membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; peripheral nervous system ganglion; sensory organ; and tooth. Orthologous to human OLFM1 (olfactomedin 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in cortex adult (RPKM 169.2), frontal lobe adult (RPKM 159.6) and 14 other tissues

Gene size: 37644bp

Exon count: 8