Mad2l1 MAD2 mitotic arrest deficient-like 1 [ Mus musculus (house mouse) ] - Gene - Data resources

56150

Mad2l1 MAD2 mitotic arrest deficient-like 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 56150)

Symbol: Mad2l1

Full name: MAD2 mitotic arrest deficient-like 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MAD2

Summary: Predicted to enable protein C-terminus binding activity and protein homodimerization activity. Involved in negative regulation of apoptotic process and positive regulation of mitotic cell cycle spindle assembly checkpoint. Acts upstream of or within mitotic sister chromatid segregation and mitotic spindle assembly checkpoint signaling. Located in several cellular components, including kinetochore; nucleus; and spindle pole. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver E14 (RPKM 32.4), CNS E11.5 (RPKM 26.2) and 15 other tissues

Orthologs: human

Gene size: 5887bp

Exon count: 5