Full name: PAX interacting (with transcription-activation domain) protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: D5Ertd149e; PTIP

Summary: This gene encodes a nuclear-localized protein that contains six BRCT1 (C-terminal of breast cancer susceptibility protein) domains. The encoded protein is involved in the repair of DNA double-strand breaks and is necessary for progression through cell division. The protein also functions in the regulation of transcription by recruiting histone methyltransferases to gene promoters bound by the sequence-specific transcription factor paired box protein 2 (Pax2). [provided by RefSeq, Mar 2013]

Expression: Ubiquitous expression in thymus adult (RPKM 12.1), ovary adult (RPKM 11.4) and 28 other tissues

Gene size: 54249bp

Exon count: 22