Full name: acyl-CoA synthetase short chain family member 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ACAS2; ACECS; ACS; ACSA; AceCS1; dJ1161H23.1

Summary: This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Expression: Broad expression in fat (RPKM 49.2), duodenum (RPKM 47.1) and 24 other tissues

Gene size: 52971bp

Exon count: 22