Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: HSY11339; SIAT7A; ST6GalNAcI; STYI

Summary: Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008]

Expression: Biased expression in colon (RPKM 93.3), small intestine (RPKM 34.8) and 7 other tissues

Gene size: 26351bp

Exon count: 12