Full name: N-glycanase 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CDDG; CDG1V; PNG-1; PNG1; PNGase

Summary: This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]

Expression: Broad expression in testis (RPKM 28.0), lymph node (RPKM 11.3) and 25 other tissues

Gene size: 71096bp

Exon count: 16