Full name: WD repeat domain 12

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: YTM1

Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.[provided by RefSeq, Dec 2008]

Expression: Ubiquitous expression in testis (RPKM 5.2), kidney (RPKM 3.9) and 25 other tissues

Gene size: 37413bp

Exon count: 13