DOCK10 dedicator of cytokinesis 10 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 55619)
Source: NCBI Gene (ID 55619)
Symbol: DOCK10
Full name: dedicator of cytokinesis 10
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: DRIP2; Nbla10300; ZIZ3
Summary: This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]
Expression: Broad expression in spleen (RPKM 10.3), lymph node (RPKM 9.4) and 22 other tissues
Orthologs: mouse
Gene size: 277379bp
Exon count: 60