Full name: hes family bHLH transcription factor 6

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: C-HAIRY1; HES-6; bHLHb41; bHLHc23

Summary: This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

Expression: Biased expression in brain (RPKM 23.5), colon (RPKM 8.2) and 12 other tissues

Gene size: 1772bp

Exon count: 4