ACER3 alkaline ceramidase 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 55331)
Source: NCBI Gene (ID 55331)
Symbol: ACER3
Full name: alkaline ceramidase 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: APHC; PHCA; PLDECO
Summary: Enables N-acylsphingosine amidohydrolase activity and metal ion binding activity. Involved in several processes, including myelination; positive regulation of cell population proliferation; and sphingolipid metabolic process. Is integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Biomarker of hepatocellular carcinoma and non-alcoholic steatohepatitis. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in fat (RPKM 8.3), brain (RPKM 5.5) and 24 other tissues
Orthologs: mouse
Gene size: 165880bp
Exon count: 16