Full name: UFM1 specific peptidase 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BHD; C4orf20; DEE106; SEMDDR

Summary: This gene encodes a highly conserved cysteine protease. The protein cleaves two C-terminal residues from ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein. Activation of ubiquitin-fold modifier 1 by the encoded protein exposes a C-terminal glycine residue that allows interaction with other proteins and transfer to its target protein. An allelic variant of this gene has been associated with Beukes hip dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Expression: Ubiquitous expression in testis (RPKM 18.7), thyroid (RPKM 17.7) and 25 other tissues

Gene size: 26428bp

Exon count: 12