Full name: protein phosphatase 3 catalytic subunit beta

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: CALNA2; CALNB; CNA2; PP2Bbeta

Summary: Enables several functions, including calmodulin binding activity; calmodulin-dependent protein phosphatase activity; and protein phosphatase 2B binding activity. Involved in calcineurin-NFAT signaling cascade; positive regulation of transcription by RNA polymerase II; and protein dephosphorylation. Located in cytoplasm. Part of calcineurin complex. Implicated in aortic valve stenosis. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in brain (RPKM 40.2), fat (RPKM 17.4) and 24 other tissues

Gene size: 59592bp

Exon count: 18