Full name: STEAP3 metalloreductase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AHMIO2; STMP3; TSAP6; dudlin-2; dudulin-2; pHyde

Summary: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Expression: Ubiquitous expression in liver (RPKM 27.2), duodenum (RPKM 11.9) and 23 other tissues

Gene size: 41819bp

Exon count: 8