Full name: dynein 2 intermediate chain 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CFAP163; DIC6; FAP163; SRPS6; SRTD8; WDR60

Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014]

Expression: Broad expression in testis (RPKM 15.3), fat (RPKM 3.5) and 21 other tissues

Gene size: 119454bp

Exon count: 35