ROPN1 rhophilin associated tail protein 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 54763)
Symbol: ROPN1
Full name: rhophilin associated tail protein 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CT91; ODF6; RHPNAP1; ROPN1A; ropporin
Summary: The protein encoded by this gene is found in the fibrous sheath of spermatazoa, where it interacts with rhophilin, a Rho GTPase binding protein. The encoded protein also can bind an A-kinase anchoring protein (AKAP110) and a calcium-binding tyrosine phosphorylation-regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer-testis antigen in hematologic malignancies. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
Expression: Restricted expression toward testis (RPKM 42.1)
Gene size: 23110bp
Exon count: 8