LEPROT leptin receptor overlapping transcript [ Homo sapiens (human) ] - Gene - Data resources

54741

LEPROT leptin receptor overlapping transcript [ Homo sapiens (human) ]
Source: NCBI Gene (ID 54741)

Symbol: LEPROT

Full name: leptin receptor overlapping transcript

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: LEPR; OB-RGRP; OBRGRP; VPS55

Summary: LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]

Expression: Ubiquitous expression in fat (RPKM 33.5), kidney (RPKM 30.3) and 25 other tissues

Orthologs: mouse

Gene size: 15340bp

Exon count: 6