Full name: Fez family zinc finger 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Fez; Fezl; Zfp312

Summary: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cell dedifferentiation; nervous system development; and positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and regulation of neuron differentiation. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; future prosencephalon; sensory organ; stomach; and thymus. Orthologous to human FEZF2 (FEZ family zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in CNS E14 (RPKM 17.8), whole brain E14.5 (RPKM 14.5) and 5 other tissues

Gene size: 9211bp

Exon count: 7