Full name: platelet-derived growth factor, C polypeptide

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110064L01Rik; PDGF-C; SCDGF; VEGF-E

Summary: Enables platelet-derived growth factor receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to amino acid stimulus; platelet-derived growth factor receptor signaling pathway; and regulation of protein phosphorylation. Located in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human PDGFC (platelet derived growth factor C). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in limb E14.5 (RPKM 8.7), ovary adult (RPKM 5.3) and 22 other tissues

Gene size: 177625bp

Exon count: 7