FBXL19 F-box and leucine rich repeat protein 19 [ Homo sapiens (human) ] - Gene - Data resources

54620

FBXL19 F-box and leucine rich repeat protein 19 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 54620)

Symbol: FBXL19

Full name: F-box and leucine rich repeat protein 19

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CXXC11; Fbl19; JHDM1C

Summary: This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Expression: Broad expression in testis (RPKM 9.4), brain (RPKM 5.2) and 23 other tissues

Orthologs: mouse

Gene size: 25933bp

Exon count: 13