Full name: plexin A2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: OCT; PLXN2

Summary: This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in ovary (RPKM 8.4), lung (RPKM 6.9) and 23 other tissues

Gene size: 222143bp

Exon count: 34