Full name: phospholipase D2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PLD1C

Summary: The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

Expression: Ubiquitous expression in esophagus (RPKM 17.0), skin (RPKM 14.6) and 23 other tissues

Gene size: 16279bp

Exon count: 25