Setd3 SET domain containing 3 [ Mus musculus (house mouse) ] - Gene - Data resources

52690

Setd3 SET domain containing 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 52690)

Symbol: Setd3

Full name: SET domain containing 3

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e

Summary: Enables N-methyltransferase activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in actin modification; peptidyl-histidine methylation; and regulation of uterine smooth muscle contraction. Acts upstream of or within positive regulation of muscle cell differentiation and positive regulation of transcription by RNA polymerase II. Located in chromatin. Orthologous to human SETD3 (SET domain containing 3, actin histidine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in cerebellum adult (RPKM 15.5), bladder adult (RPKM 14.4) and 28 other tissues

Orthologs: human

Gene size: 72927bp

Exon count: 15