PHF1 PHD finger protein 1 [ Homo sapiens (human) ] - Gene - Data resources

5252

PHF1 PHD finger protein 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 5252)

Symbol: PHF1

Full name: PHD finger protein 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MTF2L2; PCL1; PHF2; TDRD19C; hPHF1

Summary: This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Expression: Ubiquitous expression in ovary (RPKM 47.5), testis (RPKM 44.7) and 25 other tissues

Orthologs: mouse

Gene size: 6028bp

Exon count: 17