Full name: prohibitin 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HEL-215; HEL-S-54e; PHB

Summary: This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Expression: Ubiquitous expression in kidney (RPKM 68.3), colon (RPKM 44.2) and 25 other tissues

Gene size: 10831bp

Exon count: 8