Full name: peroxisomal biogenesis factor 14

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NAPP2; PBD13A; Pex14p; dJ734G22.2

Summary: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in prostate (RPKM 3.2), urinary bladder (RPKM 3.0) and 25 other tissues

Gene size: 155809bp

Exon count: 13