Full name: phosphatidylinositol glycan anchor biosynthesis class T

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CGI-06; MCAHS3; NDAP; PIG-T; PNH2

Summary: This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Expression: Ubiquitous expression in heart (RPKM 45.9), colon (RPKM 41.3) and 25 other tissues

Gene size: 10101bp

Exon count: 12