Full name: histone deacetylase 7

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HD7; HD7A; HDAC7A

Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in lung (RPKM 18.9), spleen (RPKM 18.4) and 25 other tissues

Gene size: 38623bp

Exon count: 32