Full name: zinc finger C3HC-type containing 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HSPC216; NIPA

Summary: This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]

Expression: Ubiquitous expression in testis (RPKM 3.8), lymph node (RPKM 2.0) and 25 other tissues

Gene size: 33166bp

Exon count: 13