DTL denticleless E3 ubiquitin protein ligase homolog [ Homo sapiens (human) ] - Gene - Data resources

51514

DTL denticleless E3 ubiquitin protein ligase homolog [ Homo sapiens (human) ]
Source: NCBI Gene (ID 51514)

Symbol: DTL

Full name: denticleless E3 ubiquitin protein ligase homolog

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: CDT2; DCAF2; L2DTL; RAMP

Summary: Contributes to ubiquitin-protein transferase activity. Involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Located in centrosome; cytosol; and nuclear lumen. Part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in testis (RPKM 9.8), bone marrow (RPKM 8.4) and 15 other tissues

Orthologs: mouse

Gene size: 69266bp

Exon count: 16