BFAR bifunctional apoptosis regulator [ Homo sapiens (human) ] - Gene - Data resources

51283

BFAR bifunctional apoptosis regulator [ Homo sapiens (human) ]
Source: NCBI Gene (ID 51283)

Symbol: BFAR

Full name: bifunctional apoptosis regulator

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: BAR; RNF47

Summary: Enables caspase binding activity; protein-macromolecule adaptor activity; and ubiquitin protein ligase activity. Involved in negative regulation of IRE1-mediated unfolded protein response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Acts upstream of or within negative regulation of apoptotic process. Located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in placenta (RPKM 13.9), urinary bladder (RPKM 13.0) and 25 other tissues

Orthologs: mouse

Gene size: 36286bp

Exon count: 8