SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 51100)
Symbol: SH3GLB1
Full name: SH3 domain containing GRB2 like, endophilin B1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: Bif-1; CGI-61; PPP1R70; dJ612B15.2
Summary: This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Expression: Ubiquitous expression in fat (RPKM 36.8), testis (RPKM 20.8) and 25 other tissues
Orthologs: mouse
Gene size: 43609bp
Exon count: 12