Full name: Rho guanine nucleotide exchange factor 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ASEF; ASEF1; GEF4; SMIM39; STM6

Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]

Expression: Biased expression in brain (RPKM 13.8), skin (RPKM 13.1) and 11 other tissues

Gene size: 210340bp

Exon count: 17