DEF6 DEF6 guanine nucleotide exchange factor [ Homo sapiens (human) ] - Gene - Data resources

50619

DEF6 DEF6 guanine nucleotide exchange factor [ Homo sapiens (human) ]
Source: NCBI Gene (ID 50619)

Symbol: DEF6

Full name: DEF6 guanine nucleotide exchange factor

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: IBP; IMD87; SLAT; SWAP70L

Summary: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]

Expression: Broad expression in lymph node (RPKM 23.3), bone marrow (RPKM 22.5) and 21 other tissues

Orthologs: mouse

Gene size: 23954bp

Exon count: 11