NOS3 nitric oxide synthase 3 [ Homo sapiens (human) ] - Gene - Data resources

4846

NOS3 nitric oxide synthase 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 4846)

Symbol: NOS3

Full name: nitric oxide synthase 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ECNOS; eNOS

Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Expression: Biased expression in spleen (RPKM 28.4), placenta (RPKM 4.0) and 11 other tissues

Orthologs: mouse

Gene size: 23572bp

Exon count: 28