Full name: neuromedin B receptor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BB1; BB1R; BRS1; NMB-R

Summary: This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Expression: Low expression observed in reference dataset

Gene size: 72639bp

Exon count: 5