NFIB nuclear factor I B [ Homo sapiens (human) ]
Source: NCBI Gene (ID 4781)
Symbol: NFIB
Full name: nuclear factor I B
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: CTF; HMGIC/NFIB; MACID; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription regulator inhibitor activity. Involved in brain development; negative regulation of DNA binding activity; and regulation of transcription by RNA polymerase II. Located in fibrillar center and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in fat (RPKM 8.5), brain (RPKM 6.3) and 24 other tissues
Orthologs: mouse
Gene size: 450235bp
Exon count: 22