Full name: nuclear factor of activated T cells 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NF-AT4c; NFAT4; NFATX; n339260

Summary: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]

Expression: Ubiquitous expression in testis (RPKM 17.4), lymph node (RPKM 16.5) and 25 other tissues

Gene size: 143890bp

Exon count: 12