Full name: NADH:ubiquinone oxidoreductase subunit B5

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CISGDH; SGDH

Summary: The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Expression: Ubiquitous expression in heart (RPKM 79.6), fat (RPKM 69.6) and 25 other tissues

Gene size: 22854bp

Exon count: 6