Full name: NADH:ubiquinone oxidoreductase subunit B2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AGGG; CI-AGGG

Summary: The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in heart (RPKM 93.9), kidney (RPKM 78.0) and 25 other tissues

Gene size: 9936bp

Exon count: 4