Full name: microsomal glutathione S-transferase 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GST-III

Summary: This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011]

Expression: Ubiquitous expression in heart (RPKM 114.7), fat (RPKM 75.6) and 24 other tissues

Gene size: 24903bp

Exon count: 7