Primpol primase and polymerase (DNA-directed) [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 408022)
Source: NCBI Gene (ID 408022)
Symbol: Primpol
Full name: primase and polymerase (DNA-directed)
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Ccdc111
Summary: Enables DNA primase activity. Involved in mitochondrial DNA repair and mitochondrial DNA replication. Predicted to be located in replication fork. Predicted to be active in mitochondrial matrix and nucleus. Is expressed in several structures, including aorta; brain; endocrine gland; genitourinary system; and trachea. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in limb E14.5 (RPKM 3.1), liver E14 (RPKM 3.0) and 24 other tissues
Orthologs: human
Gene size: 41669bp
Exon count: 17