Full name: renin

Gene type: protein coding

RefSeq status: PROVISIONAL

Summary: Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in angiotensin maturation. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in intermediate mesoderm; interrenal primordium; and kidney. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Apr 2022]

Gene size: 21178bp

Exon count: 9