Full name: LIM homeobox transcription factor 1 alpha

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: DFNA7; LMX1; LMX1.1

Summary: This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Expression: Low expression observed in reference dataset

Gene size: 154849bp

Exon count: 12