Mreg melanoregulin [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 381269)
Symbol: Mreg
Full name: melanoregulin
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Gm974; Wdt2; dsu
Summary: Enables phosphatidylinositol binding activity. Involved in melanosome localization; minus-end-directed organelle transport along microtubule; and phagosome maturation. Acts upstream of or within melanocyte differentiation and melanosome transport. Located in late endosome membrane and melanosome membrane. Is intrinsic component of organelle membrane. Part of protein-containing complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; liver; and lung. Orthologous to human MREG (melanoregulin). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in liver adult (RPKM 12.4), placenta adult (RPKM 7.2) and 20 other tissues
Orthologs: human
Gene size: 53082bp
Exon count: 7