Full name: inositol-tetrakisphosphate 1-kinase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ITRPK1

Summary: This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]

Expression: Ubiquitous expression in brain (RPKM 29.9), fat (RPKM 26.2) and 25 other tissues

Gene size: 179012bp

Exon count: 13