Full name: inter-alpha-trypsin inhibitor heavy chain 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: H2P; SHAP

Summary: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009]

Expression: Restricted expression toward liver (RPKM 486.6)

Gene size: 46205bp

Exon count: 21