ITGB1 integrin subunit beta 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 3688)
Symbol: ITGB1
Full name: integrin subunit beta 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB
Summary: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in fat (RPKM 292.8), gall bladder (RPKM 214.5) and 25 other tissues
Orthologs: mouse
Gene size: 57913bp
Exon count: 18