Full name: inhibin subunit alpha

Gene type: protein coding

RefSeq status: REVIEWED

Summary: This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]

Expression: Biased expression in testis (RPKM 55.0), adrenal (RPKM 22.2) and 2 other tissues

Gene size: 3402bp

Exon count: 2